From Chicklade And Pertwood, A Short Parish History by E.R. Barty, M.A., Chicklade, Old Rectory, first published December 1955:
It may be of interest to note that among “The Families of East Knoyle†was the Wren family. Dr. Christopher Wren, father of the great English architect, was Rector of Knoyle and Dean of Windsor. His son, the future Sir Christopher Wren left Wiltshire to become a student of Wadham College in 1646.
There is a probable connection between the Wren family and Chicklade as one, Elizabeth Wren, aged 87, was buried at Chicklade in 1837.